“In general, when viruses multiply, their genomes are transcribed,” said Dr. Alireza Bigleri, explaining why the Covid-19 mutations are so persistent. That means creating another version of the virus genome. At the same time, it should be noted that we have two types of virus genomes; One is RNA viruses and the other is DNA viruses.
He added: “Covid-19 disease virus is one of the RNA viruses.” RNA polymerase is an enzyme that transcribes the genome of RNA viruses, such as the Covid-19 virus, and creates new copies to replicate the virus. Now the percentage of error and possibility of error of RNA polymerase enzyme is more than DNA polymerase enzyme. Accordingly, viruses such as Rovid-19, which are RNA viruses, are more likely to cause errors.
“Accordingly, when the coronavirus enzyme transcribes the virus genome, there is a high probability of an error in it, and this error creates and causes us to see this error as a mutation.” Of course, it is important to know which part of the virus this mutation is in, and this will make you see the function of the virus differently.
The head of the Pasteur Institute of Iran said: “Sometimes several continuous mutations occur in the virus that affect the performance of the virus.” One of the places where mutations may affect the virus is through transmission. Accordingly, the virus attaches more to the receptor, which speeds up the transmission, which is the same mutation we see in the Covid-19 virus in the UK. Mutations may also affect morbidity and و.
“It is possible that the vaccines that are being made will lose their effect by mutating the virus,” Bigleri said. That is why we say that every once in a while the genome of the virus should be examined in each country to make sure that the change made does not affect the effectiveness of the vaccines made and the drugs that will be made for the disease in the future. Accordingly, we predicted from the beginning that it would not be easy to make a vaccine for the Covid-19 virus.
“One of our actions at the Pasteur Institute is to constantly monitor the status of the virus and its changes,” he said. “Currently, according to the studies we have done so far in Iran, we have not had a leap like the one seen in Britain.” Of course, we can not say that we do not have it at all. Because not all patients can be examined. What matters is what percentage of our mutations are like this.
The head of the Pasteur Institute of Iran said: “According to the studies that have been done in the country so far, we did not have a leap similar to what happened in Britain.” In Britain, it was announced that 70% of the Covid-19 viruses are with the same mutation, but we have not seen such a thing in Iran and we have not reached such a conclusion. Of course, studies in the coming months may show this change in our society, but we do not have that right now.